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2-PAM COMPOUNDS
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DeCS
Descriptor
English
:
Pralidoxime Compounds
Descriptor
Spanish
:
Compuestos de Pralidoxima
Descriptor
Portuguese
:
Compostos de Pralidoxima
Synonyms
English
:
2-PAM Compounds
Pyridine Aldoxime Methyl Compounds
Tree Number:
D02.092.570.665.535
Definition
English
:
Various salts of a quaternary ammonium oxime that reconstitute inactivated
acetylcholinesterase
, especially at the
neuromuscular junction
, and may cause
neuromuscular blockade
. They are used as
antidotes
to organophosphorus
poisoning
as
chlorides
,
iodides
, methanesulfonates (
mesylates
), or other salts.
Indexing Annotation
English
:
DF: PRALIDOXIME CPDS
History Note
English
:
65(63)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
11657
Unique Identifier:
D011220
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS